Notes on the layout of laboratory construction: Generally, it is divided into 1 P2 main laboratory, 1 first change buffer room, 1 second change buffer room, and 1 washing room. Considering that the biological laboratory should implement the requirements of both clean and non clean areas, the clean area is mainly reflected in the layout and maintenance structure of the microbiological experimental area, while the non clean area is mainly reflected in the air conditioning purification system. In terms of layout, the flow of people and logistics is separated to prevent cross infection between people and objects. That is, experimental operators enter the P2 main laboratory through the first and second buffer rooms, and experimental objects enter and exit the P2 main laboratory through two interlocking transfer windows. One interlocking transfer window is located between the main laboratory and the preparation room, and the other one is located between the main laboratory and the washing room, ensuring that clean materials are not infected, It also ensures that pollutants are cleaned as soon as possible.
Precautions for laboratory decoration: The main frame can be separated by colored steel plate glass. The combustion performance of the colored steel plate is non combustible, and the thickness of the partition glass is 5 mm. To prevent dust deposition, aluminum alloy arc pressing lines can be used for window materials. Aluminum alloy inner corners should be used for all connections on the inside, and aluminum alloy outer corners should also be used for exposed connections. The ceiling material can be made of colored steel plate. The indoor floor is made of epoxy resin material, with no gaps and good corrosion resistance.
Basic configuration considerations for laboratory planning:
The clean room needs to be equipped with 2 transfer windows to ensure the cleanliness of laboratory logistics. There is an ultraviolet lamp inside the transfer window, which can sterilize contaminated items before taking them out of the laboratory, ensuring the isolation of outdoor and indoor air. Both indoor and outdoor transfer windows can be controlled, reducing the number of times laboratory personnel enter and exit, and facilitating the transfer of items for laboratory personnel.
Automatic door closers must be installed on clean laboratory doors in accordance with national regulations.
The laboratory of the interlocking door is equipped with a set of two door interlocking electronic interlocks. When one door is not closed, the other door cannot be opened, which acts as a buffer for the airflow entering the clean room. The interlocking door is also equipped with an emergency switch, which facilitates laboratory personnel to escape the scene as soon as possible when an accident occurs.
The multifunctional controller can serve as the main control switch for the laboratory, including temperature and humidity regulation and display, start stop and start stop sequence of the supply and exhaust fans, lighting switch, UV lamp control, etc. The temperature adjustment display screen can accurately display the temperature in the laboratory, making it easy to adjust and with small temperature errors.
The pressure difference meter needs to be equipped with a pressure difference control system for the P2 laboratory according to the requirements of the biological laboratory specifications, which can display the indoor and outdoor pressure differences, and can manually control the pressure difference according to the requirements to achieve a safe range.
According to the different purposes of each laboratory, a sufficient number of single-phase nine hole sockets and three-phase four hole sockets should be configured. The sockets are all embedded and designed for airtightness, requiring a combination of dustproof, waterproof, and anti leakage power plug board.
In order to facilitate use and save power, an infrared detector is installed at the entrance of the buffer room to sense human heat, automatically turn on the fan to send clean air, and automatically delay the shutdown.
The washing room table is equipped with a washing table, drip stand, and faucet. The sink and drainage hose are all made of acid and alkali resistant PP material.
The eye washer and sensing faucet should be equipped with an eye washer on the washing table in the microbiological experimental area. When the experimenter's eyes come into contact with hazardous substances, they can be used to rinse their eyes. The sensing faucet can sense personal heat, automatically discharge water, and delay closing.
To facilitate the movement of samples and other experimental supplies by laboratory personnel, a small sample car is equipped in the washing room. The sample car is made of stainless steel structure with two layers, which is flexible and compact.
The container truck is used to dry containers after cleaning. The cleaned containers can be placed on a drip truck to drip and dry, and there is also a sink under the drip rack to collect drops.
The experimental table is a necessary equipment in the laboratory, with a table top that is resistant to acid, alkali, and corrosion. The bottom of the cabinet is equipped with drawers and cabinets to facilitate the placement of experimental supplies.
The laboratory should be equipped with one biosafety cabinet, which is mainly used as the main isolation equipment in the biological laboratory to prevent the diffusion of harmful suspended particles. The protection provided for personnel, environment, and test sample varies depending on their level. The biosafety cabinet is a front door that protects workers through vertical airflow, samples are protected through multi-layer HEPA filtration, and gases are filtered out to protect the environment.
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